Not a curative treatment for angina attacks, nor initial treatment for unstable angina or MI, nor in the pre-hospital phase or during the 1st days of hospitalization. May cause or worsen parkinsonian symptoms (tremor, akinesia, hypertonia). Discontinue use in the occurrence of movement disorders eg, parkinsonian symptoms, restless leg syndrome, tremors, gait instability. Falls may occur, related to gait instability or hypotension particularly in patients on antihypertensive treatment. Moderate renal impairment. Pregnancy & lactation. Childn <18 yr. Elderly >75 yr.