As rarely shock may occur, monitor carefully. In such a case, discontinue therapy.
As rarely Stevens-Johnson syndrome, erythema multiforme, Lyell's syndrome (toxic epidermal necrolysis) may occur, monitor carefully. In such case, discontinue the therapy.
When the symptoms such as pruritus, rash (erythema, etc) fever, urticaria, swelling of lymph node, arthralgia, anaphylactic reaction, etc. may occur, discontinue the therapy.
Rarely, severe renal disorder such as acute renal insufficiency may occur. Thus, monitor carefully, and discontinue the therapy in such a case.
Rarely, decreased hemoglobin concentration, anemia, agranulocytosis, leukopenia, thrombocytopenia, occasionally, neutropenia and eosinophilia may occur. And it is reported that hemolytic anemia have occurred following administration of other cephems.
Occasionally, rise in GOT, GPT, AL-P levels, rarely, rise in bilirubin, LDH and GPT levels may occur.
Rarely, symptoms of pseudomembranous colitis may appear, when abnormal pain and frequent diarrhea occur, discontinue the therapy immediately. Sometimes, nausea, diarrhea. Rarely, vomiting, anorexia, etc. may occur.
Rarely, fever, coughing, dyspnea, and interstitial penumonia accompanying eosinophilia, PIE syndrome, etc may occur. In such case, discontinue the therapy and administer corticosteroids.
Rarely, candidal intertrigo may occur.
Deficiency symptoms of vitamin:
Rarely, deficiency symptoms of vitamin K (hypoprothrombinemia, tendency of bleeding, etc) and vitamin B (glossitis, stomatitis, anorexia, neuritis, etc) may occur.
Rarely, sense of paralysis may occur.