Saga Lab


Pasteur Pharma


Concise Prescribing Info
Levofloxacin hemihydrate
Acute bacterial sinusitis, complicated & uncomplicated skin & skin structure infections, chronic bacterial prostatitis, complicated & uncomplicated UTI, acute pyelonephritis. Acute bacterial exacerbation of chronic bronchitis, nosocomial pneumonia, community-acquired pneumonia due to methicillin susceptible microorganisms.
Dosage/Direction for Use
Adult Resp, uncomplicated skin infection & chronic prostate infection 500 mg once daily. 750 mg once daily for certain types of pneumonia. Treatment of resp infection typically last 5-14 days; uncomplicated skin infection for 7-10 days; chronic prostate infection last for 28 days. Complicated skin infection 750 mg once daily for 7-14 days. Kidney & urinary infection 250 mg once daily for 3-10 days.
May be taken with or without food: Ensure adequate fluid intake.
Hypersensitivity to levofloxacin or other quinolones.
Special Precautions
Discontinue immediately at the 1st appearance of skin rash or any other sign of hypersensitivity; if hypoglycemic reaction occurs. May increase intracranial pressure & CNS stimulation. Adequate hydration to prevent formation of a highly concentrated urine. Known or suspected CNS disorder or in the presence of the risk factors that may predispose to seizures or lower the seizure threshold. Disturbance of blood glucose including symptomatic hyper/hypoglycemia. Monitor blood glucose in diabetic patients receiving concomitant treatment w/ hypoglycemic agent (eg, glyburide/glibenclamide) or w/ insulin. Torsade de pointes. Patients w/ known prolongation of QT interval, uncorrected hypokalemia, & receiving class IA (quinidine, procainamide), class III (amiodarone, sotalol) antiarrhythmic agents. Childn.
Adverse Reactions
Ascites, allergic reaction, asthenia, edema, fever, headache, hot flashes, flu-like symptoms, leg pain, malaise, rigors, substernal chest pain, syncope, multiple organ failure, changed temp sensation, w/drawal syndrome; cardiac failure, HTN, aggravation of HTN, hypotension, postural hypotension; convulsion, hyperesthesia, hyperkinesia, hypertonia, hypoesthesia, involuntary muscle contraction, migraine, paresthesia, paralysis, speech disorder, stupor, tremor, vertigo, encephalopathy, abnormal gait, leg cramps, intracranial HTN, ataxia; dry mouth, dysphagia, esophagitis, GERD, GI hemorrhage, glossitis, intestinal obstruction, pancreatitis, tongue edema, melena, stomatitis; abnormal hepatic function, cholecystitis, cholelithiasis, increased hepatic enzyme, hepatic failure, jaundice; airways obstruction, aspiration, asthma, bronchitis, bronchospasm, COPD, coughing, hemoptysis, epistaxis, hypoxia, laryngitis, pleural effusion, pleurisy, pneumonitis, pneumonia, pneumothorax, pulmonary edema.
Drug Interactions
May interfere absorption w/ antacid containing Mg, Al, sucralfate, metal cation eg, Fe & multivitamin w/ Zn.
MIMS Class
ATC Classification
J01MA12 - levofloxacin ; Belongs to the class of fluoroquinolones. Used in the systemic treatment of infections.
Xovell FC tab 500 mg
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