benzathine benzylpenicillin




Cathay Drug
Concise Prescribing Info
Benzathine benzylpenicillin
Diphtheria, pharyngitis, rheumatic fever, spleen disorders & syphilis.
Dosage/Direction for Use
Upper resp infections Adult 1,200,000 u. Childn ≥27.3 kg body wt 900,000 u, ≤27.3 kg body wt & infant 300,000-600,000 u. Doses to be given as single IM doses w/ a frequency of 2 inj in 10 days. Syphilis 2,400,000 u as a single IM dose, to be given once a wk for 3 wk. Congenital syphilis Childn 2-12 yr ¼-1/3 the adult dose, ≤2 yr & infant 50,000 u/kg body wt as a single IM dose. To be taken once a wk for 2 wk. Prophylaxis of rheumatic fever & Strep pharyngitis 1,200,000 u as a single IM dose every 3 wk.
Hypersensitivity to penicillins. Do not inject into or near an artery or nerve.
Special Precautions
Hypersensitivity to cephalosporins & other β-lactam antibiotics, poor renal function. IV & intrathecal inj should be avoided. History of cardiac decompensation, severe heart disease.
Adverse Reactions
Skin rash, anaphylaxis, hemolytic anemia, angioedema, urticaria, acute interstitial nephritis.
Drug Interactions
Bacteriostatic antibacterial agents, probenecid.
MIMS Class
ATC Classification
J01CE08 - benzathine benzylpenicillin ; Belongs to the class of beta-lactamase sensitive penicillins. Used in the systemic treatment of infections.
Zalpen powd for inj 1200000 u
10 × 1's (P2,130.24/box)
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