Zopip

Zopip

piperacillin + tazobactam

Manufacturer:

Macheal Lab

Distributor:

Suhitas
Concise Prescribing Info
Contents
Per 2 g/250 mg powd for inj Piperacillin Na 2 g, tazobactam Na 250 mg. Per 4 g/500 mg powd for inj Piperacillin Na 4 g, tazobactam Na 500 mg
Indications/Uses
For documented multidrug resistant gm -ve infections due to organisms proven or suspected to be piperacillin-tazobactam except CNS infections; polymicrobial infections (eg, mixed aerobic & anaerobic infections in which other agents have insufficient activity or are contraindicated due to toxic potential.
Dosage/Direction for Use
IV/IM Adult Serious complicated infections 200-300 mg/kg daily in divided doses. Usual dose: 3-4 g IV every 4-6 hr. Mild or uncomplicated infections 100-125 mg/kg daily. Usual dose: 2 g IV every 6-8 hr or 4 g IV every 12 hr or 2 g IM every 8-12 hr. Uncomplicated gonorrhea 2 g single dose IM. Surgical prophylaxis 2 g pre-op.
Contraindications
Hypersensitivity to penicillins, cephalosporins or β-lactamase inhibitors.
Special Precautions
Bleeding, clotting time, super infection, organ system function assessment, fever & rash in cystic fibrosis patients, patients w/ syphilis, neutropenia & leukopenia may occur in prolonged use. Possibility of hypokalemia. Pregnancy & lactation.
Adverse Reactions
Diarrhea, nausea, vomiting, rash, leukopenia, neutropenia, thrombocytopenia, hypersensitivity reactions, headache, insomnia, hypotension, phlebitis, thrombophlebitis, constipation, dyspepsia, jaundice, stomatitis, increased serum creatine, pruritus, urticaria & fever.
Drug Interactions
Anticoagulants, probenecid, vecuronium, aminoglycosides, methotrexate.
MIMS Class
ATC Classification
J01CR05 - piperacillin and beta-lactamase inhibitor ; Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections.
Presentation/Packing
Form
Zopip powd for inj 2 g/250 mg
Packing/Price
1's
Form
Zopip powd for inj 4 g/500 mg
Packing/Price
1's
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