Zyclor

Zyclor

aciclovir

Manufacturer:

Furen Pharma

Distributor:

International Apex
Concise Prescribing Info
Contents
Aciclovir
Indications/Uses
Treatment of initial & recurrent mucocutaneous HSV-1 & HSV-2 infections & severe 1st episodes of genital herpes infections in immunocompetent individuals. HSV encephalitis & neonatal HSV infections.
Dosage/Direction for Use
Max of 20 mg/kg every 8 hr by slow IV infusion, at constant rate over at least 1 hr.
Contraindications
Special Precautions
Neurologic abnormalities & patients w/ serious renal or electrolyte abnormalities or substantial hypoxia. Risk of aciclovir-induced renal impairment &/or reversible CNS symptoms. Avoid IM & SC inj as well as rapid or bolus IV inj. Elderly & patients w/ existing renal impairment.
Adverse Reactions
Inflammation or phlebitis at inj site. Renal failure, fever & pain.
Drug Interactions
Caution w/ intrathecal methotrexate or interferon. Increased risk of renal impairment w/ nephrotoxic drugs. Renal clearance blockade w/ probenecid.
MIMS Class
ATC Classification
J05AB01 - aciclovir ; Belongs to the class of nucleosides and nucleotides excluding reverse transcriptase inhibitors. Used in the systemic treatment of viral infections.
Presentation/Packing
Form
Zyclor lyo powd for inj 250 mg
Packing/Price
10 × 1's
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