Zyrrigin

Zyrrigin

cetirizine

Manufacturer:

Unison

Distributor:

JustRight Healthcare
Concise Prescribing Info
Contents
Cetirizine HCl
Indications/Uses
Relief of nasal & ocular symptoms of seasonal & perennial allergic rhinitis. Symptomatic relief of chronic idiopathic urticaria.
Dosage/Direction for Use
Tab Adult & adolescent >12 yr 10 mg once daily. Childn 6-12 yr 5 mg bid. Syr Adult & adolescent >12 yr 10 mL once daily. Childn 6-12 yr 5 mL bid, 2-6 yr 2.5 mL bid. Renal impairment CrCl ≥80 mL/min 10 mg once daily, 50-79 mL/min 10 mg once daily, 30-49 mL/min 5 mg once daily, <30 mL/min 5 mg once every 2 days.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to cetirizine, hydroxyzine or any piperazine derivatives. Severe renal impairment at CrCl <10 mL/min or end-stage renal disease. Tab: Rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Not to be used in childn <6 yr.
Special Precautions
Patients w/ predisposition factors of urinary retention (eg, spinal cord lesion, prostatic hyperplasia), epileptic patients & patients who are at risk of convulsions. Observe a wash-out period of 3 days before performing allergy skin tests. Pruritus &/or urticaria. Alcohol. Pregnancy & lactation. Childn.
Adverse Reactions
Rarely, hypersensitivity, aggression, confusion, depression, hallucinations, insomnia, convulsions, tachycardia, abnormal hepatic function (increased transaminases, alkaline phosphatase, γ-GT & bilirubin), urticaria, edema, increased wt.
Drug Interactions
Pseudoephedrine or theophylline (400 mg/day). Alcohol or other CNS depressants.
MIMS Class
Antihistamines & Antiallergics
ATC Classification
R06AE07 - cetirizine ; Belongs to the class of piperazine derivatives used as systemic antihistamines.
Presentation/Packing
Form
Zyrrigin film-coated tab 10 mg
Packing/Price
10 × 10's
Form
Zyrrigin syr 5 mg/5 mL
Packing/Price
60 mL x 1's
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