1. AA Pharma Nifedipine is contraindicated in pregnancy and women of child-bearing potential. Fetal malformations and adverse effects on pregnancy have been reported in animals.
An increase in the number of fetal mortalities and resorptions occurred after the administration of 30 and 100 mg/kg nifedipine to pregnant mice, rats and rabbits. Fetal malformations occurred after the administration of 30 and 100 mg/kg nifedipine to pregnant mice and 100 mg/kg to pregnant rats.
2. Unstable angina pectoris.
3. Acute myocardial infarction (within the first 4 weeks).
4. Secondary prevention of myocardial infarction, as there is no convincing evidence of efficacy in these conditions and there are concerns about safety.