Each vial contains 50 mg of brentuximab vedotin.
After reconstitution (see Special precautions for disposal and other handling under Cautions for Usage), each ml contains 5 mg of brentuximab vedotin.
ADCETRIS is an antibody-drug conjugate composed of a CD30-directed monoclonal antibody (recombinant chimeric immunoglobulin G1 (IgG1), produced by recombinant DNA technology in Chinese Hamster ovary cells) that is covalently linked to the antimicrotubule agent monomethyl auristatin E (MMAE).
Excipients with known effect: Each vial contains approximately 13.2 mg of sodium.
Excipients/Inactive Ingredients: Citric acid monohydrate, Sodium citrate dihydrate, α,α-Trehalose dihydrate, Polysorbate 80.