Alemtuzumab - intravenous

Patient Medicine Information
Why do I need this medicine?
Alemtuzumab is used to treat B-cell chronic lymphocytic leukaemia or B-CLL (a type of cancer where the bone marrow produces too many white blood cells called lymphocytes).

This medicine is also used to treat multiple sclerosis (scars or lesions in the brain and spinal cord).
How do I use this medicine?
Alemtuzumab injection is to be given intravenously (into the vein). It is delivered directly into the bloodstream via the blood vessel.

Your doctor or nurse will administer the injection for you.
What should I do if I have forgotten to use this medicine?
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Alemtuzumab.

If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • active infection of any type
  • HIV infection
as Alemtuzumab may not be suitable for you.
What should I take note of while using this medicine?
Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. Your doctor may also need to do routine blood and urine tests while you are being treated with Alemtuzumab as this medicine may increase the risk of autoimmune conditions (your own immune system attacking your body). These tests are needed for 48 months after you have stopped the treatment.

This medicine may increase the risk of getting infections e.g. fungal infection in the mouth and vagina. Maintain good hygiene as this is important in managing fungal infections.

Inform your doctor if you have been recently vaccinated. Do not receive any vaccinations without first asking your doctor.

Let your doctor know if you are pregnant or breastfeeding.
What side effects could I experience?
This medicine may cause any of the following side effects: headache, nausea, vomiting, rash, chills, dizziness, loss of appetite, diarrhoea, dehydration, fever and fatigue.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • infusion reaction e.g. difficulty breathing, abnormal heartbeat and heart attack
  • bleeding problems
  • kidney disease
  • serious infections
  • autoimmune cytopenia (reduction in the number of mature blood cells)
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • live vaccines e.g. BCG
  • myelosuppressive agents e.g. deferiprone, dipyrone
  • medicines used in organ transplant or certain immune disorders e.g. pimecrolimus, tacrolimus
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in the refrigerator, between 2-8 °C. Do not allow to freeze. If frozen, this medicine will become ineffective and should not be used.

Protect from light. Light may cause the medication to lose some of its effectiveness.

Do not use this medicine if it becomes cloudy or if it has changed in colour.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on alemtuzumab - intravenous and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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