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Apidra

Apidra

insulin glulisine

Manufacturer:

sanofi-aventis

Distributor:

DKSH
Concise Prescribing Info
Contents
Insulin glulisine
Indications/Uses
Adults, adolescents & childn ≥6 yr w/ DM, where treatment w/ insulin is required.
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Dosage/Direction for Use
SC Individualized dosing by SC inj or continuous SC pump infusion.
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Overdosage
View Apidra overdosage for action to be taken in the event of an overdose.
Administration
Should be taken with food: Administer shortly (0-15 min) before or soon after meals.
Contraindications
Hypersensitivity. Hypoglycaemia.
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Special Precautions
Transfer to another type or brand of insulin should be done under strict medical supervision & may require change in dose. Inadequate dosing or discontinuation of treatment. Adjust dose if to undertake increased physical activity or change in usual meal plan. Contains metacresol. Renal & hepatic impairment. May affect ability to drive & operate machinery. Pregnancy & lactation. Childn <6 yr.
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Adverse Reactions
Hypoglycaemia; inj site reactions, local hypersensitivity reactions.
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Drug Interactions
May enhance blood glucose-lowering activity & increase susceptibility of hypoglycaemia by other oral antidiabetics, ACE inhibitors, disopyramide, fibrates, fluoxetine, MAOIs, pentoxifylline, propoxyphene, salicylates, sulfonamide antibiotics. May reduce blood glucose-lowering activity by corticosteroids, danazol, diazoxide, diuretics, glucagon, INH, phenothiazine derivatives, somatropin, sympathomimetics (eg, epinephrine, salbutamol, terbutaline), thyroid hormones, estrogens, progestins (eg, OCs), PIs & atypical antipsychotics (eg, olanzapine, clozapine). May potentiate or weaken blood glucose-lowering activity w/ β-blockers, clonidine, lithium salts or alcohol. Hypoglycaemia may sometimes followed by hyperglycaemia w/ pentamidine. Reduced or absent signs of adrenergic counterregulation w/ sympatholytics eg, β-blockers, clonidine, guanethidine & reserpine.
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Caution For Usage
For caution against possible variation of physical aspect of medicine... Click to view Apidra detailed prescribing information
Storage
View Apidra storage conditions for details to ensure optimal shelf-life.
Description
View Apidra description for details of the chemical structure and excipients (inactive components).
Action
View Apidra mechanism of action for pharmacodynamics and pharmacokinetics details.
ATC Classification
A10AB06 - insulin glulisine ; Belongs to the class of fast-acting insulins and analogues. Used in the treatment of diabetes.
Presentation/Packing
Form
Apidra soln for inj 100 u/mL
Packing/Price
(SoloStar) 3 mL x 1's
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