Transfer to another type or brand of insulin should be done under strict medical supervision & may require change in dose. Inadequate dosing or discontinuation of treatment. Perform continuous inj rotation to reduce the risk of developing lipodystrophy & cutaneous amyloidosis. Monitor blood glucose after change in inj site & dose adjustment. Adjust dose if to undertake increased physical activity or change in usual meal plan. Contains metacresol. Possible cardiac failure w/ insulin in patients w/ risk factors for development of cardiac heart failure. Renal & hepatic impairment. May affect ability to drive & operate machinery. Pregnancy & lactation. Childn <6 yr.
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