Apidra

Apidra

insulin glulisine

Manufacturer:

sanofi-aventis

Distributor:

DKSH
Concise Prescribing Info
Contents
Insulin glulisine
Indications/Uses
Adults, adolescents & childn ≥6 yr w/ DM, where treatment w/ insulin is required.
Dosage/Direction for Use
SC Individualized dosing by SC inj or continuous SC pump infusion.
Administration
Should be taken with food: Administer shortly (0-15 min) before or soon after meals.
Contraindications
Special Precautions
Transfer to another type or brand of insulin should be done under strict medical supervision & may require change in dose. Inadequate dosing or discontinuation of treatment. Adjust dose if to undertake increased physical activity or change in usual meal plan. Contains metacresol. Renal & hepatic impairment. May affect ability to drive & operate machinery. Pregnancy & lactation. Childn <6 yr.
Adverse Reactions
Hypoglycaemia; inj site reactions, local hypersensitivity reactions.
Drug Interactions
May enhance blood glucose-lowering activity & increase susceptibility of hypoglycaemia by other oral antidiabetics, ACE inhibitors, disopyramide, fibrates, fluoxetine, MAOIs, pentoxifylline, propoxyphene, salicylates, sulfonamide antibiotics. May reduce blood glucose-lowering activity by corticosteroids, danazol, diazoxide, diuretics, glucagon, INH, phenothiazine derivatives, somatropin, sympathomimetics (eg, epinephrine, salbutamol, terbutaline), thyroid hormones, estrogens, progestins (eg, OCs), PIs & atypical antipsychotics (eg, olanzapine, clozapine). May potentiate or weaken blood glucose-lowering activity w/ β-blockers, clonidine, lithium salts or alcohol. Hypoglycaemia may sometimes followed by hyperglycaemia w/ pentamidine. Reduced or absent signs of adrenergic counterregulation w/ sympatholytics eg, β-blockers, clonidine, guanethidine & reserpine.
ATC Classification
A10AB06 - insulin glulisine ; Belongs to the class of fast-acting insulins and analogues. Used in the treatment of diabetes.
Presentation/Packing
Form
Apidra soln for inj 100 u/mL
Packing/Price
(SoloStar) 3 mL x 1's
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