Infections of the upper resp or genitourinary tracts, skin & soft tissues due to susceptible strains Adult 250 mg every 8 hr.
Childn <20 kg 20 mg/kg/day in divided doses every 8 hr.
Severe infections or infections associated w/ organisms where sensitivity determinations require higher blood conc Adult 500 mg every 8 hr.
Childn <20 kg 40 mg/kg/day in divided doses every 8 hr.
Infections of the lower resp tract due to susceptible strains of the causative organism & acute otitis media Adult 500 mg every 8 hr.
Childn <20 kg 40 mg/kg/day in divided doses every 8 hr.
Urethritis due to non-penicillinase producing N. gonorrheae Adult & childn >45 kg 3 g as single oral dose; 1 g of oral probenecid should be administered concomitantly as well as appropriate therapy for presumptive or proven infection w/
C. trachomatis.
Childn <45 kg 50 mg/kg as single dose (max: 3 g).
Prevention of endocarditis 3 g 1 hr before procedure, then 1.5 g 6 hr after initial dose.
Childn 50 mg/kg 1 hr before the procedure, then 25 mg/kg 6 hr after the initial dose.