Apo-Carbamazepine Special Precautions





Full Prescribing Info
Special Precautions
Hematological and Other Adverse Reactions: Conduct complete blood studies, including platelet counts, and evaluation of hepatic and renal function and urinalysis before instituting treatment. Maintain careful clinical and laboratory supervision throughout treatment, including frequent performance of complete blood counts, in order to detect any early signs or symptoms of blood dyscrasia. Should any signs or symptoms or abnormal laboratory findings suggestive of blood dyscrasia or liver disorder occur, immediately discontinue use of carbamazepine until the case is carefully reassessed.
Urinary Retention and Increased Intraocular Pressure: Because of its anticholinergic action, give carbamazepine cautiously. If at all, to patients with increased intraocular pressure or urinary retention, follow such patients closely.
Behavioral Disorders: Because it is closely related to the other tricyclic drugs, there is some possibility that carbamazepine might activate a latent psychosis, or in elderly patients, produce agitation or confusion, especially when combined with other drugs. Exercise caution in use with alcoholics.
Cardiovascular Disorders: Use carbamazepine cautiously in patients with a history of coronary artery disease, organic heart disease, or congestive failure.
Perform an ECG before administering carbamazepine to exclude the possibility that the patient has an atrio-ventricular block whenever a defect in the conductive system is suspected.
Occupational hazards: Dizziness and drowsiness are possible side effects. Warn patients about possible hazards.
Oral Contraceptive Use: Efficacy of oral contraceptives may be diminished for patients being treated with carbamazepine. Advise patients to use an alternative non-steroidal contraceptive method.
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