Apo-ISDN

Apo-ISDN

isosorbide dinitrate

Manufacturer:

Apotex

Distributor:

Pharmaforte
Concise Prescribing Info
Contents
Isosorbide dinitrate
Indications/Uses
Prophylaxis of ischemic heart pain associated w/ chronic angina.
Dosage/Direction for Use
Individualized dosage. SL 5-10 mg 2-4 hrly. Supplemented as required. Oral 5-30 mg qds.
Administration
Should be taken on an empty stomach: Take 30 min before meals.
Contraindications
Hypersensitivity to isosorbide or known idiosyncratic reaction to organic nitrates. Increased intracranial pressure (eg, head trauma or cerebral hemorrhage). W/hold treatment in presence of cardiogenic shock or risk of shock developing.
Special Precautions
Early days of acute phase of MI. Do not discontinue abruptly. May develop tolerance & cross-tolerance to other nitrates & nitrites. Glaucoma. Hypotension. Pregnancy.
Adverse Reactions
Headache (severe & persistent). Drug &/or exfoliative dermatitis, weakness & transient episodes of dizziness, cutaneous vasodilation w/ flushing.
Drug Interactions
Antagonise effects of histamine or epinephrine, acetylcholine & similar agents.
MIMS Class
ATC Classification
C01DA08 - isosorbide dinitrate ; Belongs to the class of organic nitrate vasodilators. Used in the treatment of cardiac disease.
Presentation/Packing
Form
Apo-ISDN tab 10 mg
Packing/Price
1000's
Form
Apo-ISDN SL tab 5 mg
Packing/Price
100's
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