Apo-Nifed

Apo-Nifed

nifedipine

Manufacturer:

Apotex

Distributor:

Pharmaforte
Concise Prescribing Info
Contents
Nifedipine
Indications/Uses
Vasospastic & chronic stable angina pectoris, essential HTN, hypertensive emergency, Raynaud's syndrome.
Dosage/Direction for Use
Initially 10 mg tds. Usual dose: 10-20 mg tds. May increase to 20-30 mg tds-qds. Max: 120 mg.
Administration
May be taken with or without food: Avoid grapefruit juice.
Contraindications
Pregnancy, lactation. Apo-Nifed: Unstable angina pectoris, acute MI (w/in the 1st 4 wk), secondary prevention of MI.
Special Precautions
Poor cardiac reserve; diabetes; heart failure; severe aortic stenosis; elderly. Monitor BP & heart rate during therapy.
Adverse Reactions
Dizziness, flushing & heat sensation, headache; hypotension; peripheral oedema, lightheadedness & giddiness, nausea & vomiting, GI distress. Rarely, hepatitis; rash; muscle cramps; nephrotic syndrome; acute psychosis; gingival hyperplasia.
Drug Interactions
Enhances antihypertensive effect of β-blockers, hypotensive agents. Bioavailability increased w/ cimetidine, ranitidine. β-adrenergic-blockers.
ATC Classification
C08CA05 - nifedipine ; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.
Presentation/Packing
Form
Apo-Nifed cap 10 mg
Packing/Price
100's
Form
Apo-Nifed cap 5 mg
Packing/Price
100's
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