Apo-Prazo

Apo-Prazo

prazosin

Manufacturer:

Apotex

Distributor:

Pharmaforte
Concise Prescribing Info
Contents
Prazosin HCl
Dosage/Direction for Use
0.5 mg, increase gradually w/ 0.5 mg given bd or tds for at least 3 days. May be further increase to 1 mg given bd-tds for at least 3 days. Continue incremental increases until desired effect achieved. Max: 20 mg daily. Patients receiving diuretic therapy, other antihypertensive agents Reduce dose of the particular agent & initiate prazosin at 0.5 mg bd or tds. Patients on prazosin to whom other antihypertensive agents added Reduce dose to 1 or 2 mg bd or tds. Moderate to severe renal impairment Initially 0.5 mg daily, increase dose gradually.
Administration
May be taken with or without food: Starting dose is best taken w/ dinner, at least 2-3 hr before retiring. Maintenance doses may be taken w/ or w/o meals.
Contraindications
Hypersensitivity to prazosin HCl or quinazolines.
Special Precautions
Syncopal episodes, acute hypotension. Moderate to severe renal impairment. Alcohol consumption. False +ve results in screening tests for pheochromocytoma. May affect ability to drive or operate machinery. Not recommended in childn <12 yr. Pregnancy & lactation.
Adverse Reactions
Postural dizziness, nausea, drowsiness, headache, palpitations, dry mouth, weakness, fatigue/malaise.
Drug Interactions
Effect enhanced by other hypotensive agents including diuretics.
ATC Classification
C02CA01 - prazosin ; Belongs to the class of alpha-adrenoreceptor antagonists, peripherally-acting antiadrenergic agents. Used in the treatment of hypertension.
Presentation/Packing
Form
Apo-Prazo tab 5 mg
Packing/Price
100's
Form
Apo-Prazo tab 2 mg
Packing/Price
100's
Form
Apo-Prazo tab 1 mg
Packing/Price
100's
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