0.5 mg, increase gradually w/ 0.5 mg given bd or tds for at least 3 days. May be further increase to 1 mg given bd-tds for at least 3 days. Continue incremental increases until desired effect achieved. Max: 20 mg daily. Patients receiving diuretic therapy, other antihypertensive agents
Reduce dose of the particular agent & initiate prazosin at 0.5 mg bd or tds. Patients on prazosin to whom other antihypertensive agents added
Reduce dose to 1 or 2 mg bd or tds. Moderate to severe renal impairment
Initially 0.5 mg daily, increase dose gradually.