Increased risk of heart attack or stroke in high doses (2,400 mg daily) or prolonged treatment. Do not exceed the recommended dose & duration. Fructose intolerance, glucose-galactose malabsorption, sucrose-isomaltase insufficiency. Patients w/ diabetes. History of GI bleeding & perforation. Asthma, chronic rhinitis, heart, liver or kidney diseases, heart failure, uncontrolled high BP, dehydration. Concomitant use w/ drugs for high BP, heart diseases & blood thinners. Can mask symptoms of underlying infections.