Cushing's syndrome, adrenal suppression, growth retardation, decreased bone mineral density, cataract, glaucoma & a wide range of psychiatric/behavioural effects. Increased susceptibility to infections & their severity. Liver function disorders. Visual disturbance. Patients w/ TB, HTN, DM, osteoporosis, peptic ulcer (gastric or duodenal ulcer), glaucoma, cataract; family history of diabetes, glaucoma. Monitor for infections or skin irritations. Do not give live vaccines to persons w/ chronic glucocorticosteroid use. May cause suppression of the hypothalamic-pituitary-adrenal axis & reduce the stress response (supplementary systemic glucocorticoid treatment is recommended where patients are subject to surgery or other stresses). Concomitant use w/ ketoconazole or other CYP3A inhibitors. Systemic glucocorticoid-like effects (higher than recommended doses). Pregnancy & lactation.
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