Adult males including the elderly: 50-mg: one tablet (50 mg) once a day. Treatment with Casodex should be started at the same time as treatment with an LHRH analogue or surgical castration.
150-mg: The dosage is one 150 mg tablet to be taken orally once a day.
Casodex 150 mg should be taken continuously for at least 2 years or until disease progression.
Renal impairment: No dosage adjustment is necessary for patients with renal impairment.
Hepatic impairment: No dosage adjustment is necessary for patients with mild hepatic impairment. Increased accumulation may occur in patients with moderate to severe hepatic impairment (see Precautions).
50-mg: Children: Casodex is contraindicated in children.