ILDong Pharm


Concise Prescribing Info
Ciprofloxacin HCl
Infections of the resp tract, ENT, mouth, teeth & jaws, kidneys &/or efferent urinary tract; genital organs including gonorrhoea, GIT, biliary tract, wounds & soft tissues, bones & joints, O & G. Septicaemia, meningitis, peritonitis, ophth infections.
Dosage/Direction for Use
Adult 250-500 mg daily in 2 divided doses. Renal impairment ½ the normal dose.
May be taken with or without food: May be taken w/ meals to minimise GI discomfort. Do not take w/ antacids, Fe or dairy products.
Hypersensitivity. History of hypersensitivity, tendinitis, tendon rupture to quinolones. Hepatic disease. Pregnancy & lactation. Childn & adolescents (<18 yr).
Special Precautions
Discontinue immediately at the 1st appearance of signs or symptoms of any serious AR; if pain, inflammation, tendon rupture (particularly affecting the achilles tendon) occur; peripheral neuropathy symptoms. Patients w/ known risk factors for QT interval prolongation eg, congenital long QT syndrome, concomitant use of QT interval-prolonging drugs, uncorrected electrolyte imbalance, elderly, cardiac disease. Consult a specialist immediately if vision becomes impaired or any effects on the eyes are experienced; in case of sudden abdominal, chest or back pain. Increased risk of aortic aneurysm & dissection after intake, particularly in the elderly. Patients w/ positive family history of aneurysm disease, or in those diagnosed w/ preexisting aortic aneurysm &/or dissection, or in presence of other risk factors or conditions predisposing for aortic aneurysm & dissection. Increased risk of psychiatric AR; discontinue immediately if these reactions occur. Carefully monitor blood glucose; discontinue use if hypoglycaemic reaction occurs. Patients w/ or w/ a history of convulsive disorder eg, epilepsy; w/ cerebral blood flow disturbances; vein system injury. Severe renal disorder. Elderly.
Adverse Reactions
Elevated BUN & serum creatinine, acute renal failure, nephritis, crystalluria; myalgia, asthenia, striated muscle sychysis; interstitial pneumonia attended w/ fever, cough, dyspnea, abnormal chest x-ray, elevated eosinophilia.
Drug Interactions
May elevate serum conc w/ theophylline. Concomitant use w/ nonsteroidal anti-inflammatory phenylacetic/propionic acid derivatives (eg, fenbufen). Absorption may be interfered by Al- or Mg-containing antacids. Elevated serum creatinine levels w/ cyclosporine. QT interval-prolonging drugs (eg, class IA & III antiarrhythmics, TCAs, macrolides, antipsychotics).
MIMS Class
ATC Classification
J01MA02 - ciprofloxacin ; Belongs to the class of fluoroquinolones. Used in the systemic treatment of infections.
Cycin tab 250 mg
Cycin tab 500 mg
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