Not for threatened miscarriage. Discontinue treatment in the event of a missed miscarriage; if w/ suspected MI, cerebrovascular disorders, arterial or venous thromboembolism, thrombophlebitis or retinal thrombosis. May increase risk of thromboembolism in women w/ generally recognized risk factors eg, personal or family history. Closely observe patients w/ history of depression; conditions that might be influenced by degree of fluid retention (eg, epilepsy, migraine, asthma, cardiac or renal dysfunction); diabetic patients while receiving therapy. Patients w/ hormone-sensitive conditions. Use rectally if barrier methods of contraception are used or if patients suffer from vag infection (especially moniliasis) or recurrent cystitis. Use vaginally if patients suffer from colitis or fecal incontinence. Hepatic dysfunction. Not to be used during pregnancy (except as indicated during the 1st trimester as part of an ART treatment) & lactation. Childn. Elderly >65 yr.