Zuellig Pharma
Concise Prescribing Info
Situations where lowering of sex steroid serum levels to castrate level is desired eg, prostate cancer, endometriosis or uterine myoma or assisted reproduction techniques eg, in vitro fertilisation (IVF). As a diagnostic agent for prostate carcinoma. Men: Symptomatic treatment of an advanced hormone-dependent prostate carcinoma. Women: Endometriosis, uterine myoma, IVF.
Dosage/Direction for Use
Central precocious puberty 0.5 mg SC inj/day for 7 days, followed by 0.1 mg SC inj/day. IVF 7-10 days w/ 0.5 mg SC, followed by 0.1 mg SC daily.
Hormone-independent prostate carcinoma. Clinically manifest osteoporosis or risk of osteoporosis (eg, reduced bone density). Pregnancy & lactation.
Special Precautions
Monitor sex steroid serum levels. Hormonal methods of contraception & prep containing estrogens should not be used during therapy. Men: The initial transient increase of serum testosterone has been associated w/ a temporary aggravation of secondary symptoms of the disease (eg, urinary obstruction, skeletal pain due to metastases, compression of the spinal cord, muscular fatigue & lymphatic oedema of the legs). Women: Non-hormonal methods of contraception & prep containing estrogens should not be used during therapy. Non-pregnancy should be confirmed prior to treatment.
Adverse Reactions
In men: Hot flushes, impotence & loss of libido, rarely gynaecomastia & testicular atrophy. In women: Hot flushes, bleeding or spotting, vag dryness &/or dyspareunia. In men & women: Local reactions at inj site, mild allergic reaction, headache, fatigue & sleep disturbances.
MIMS Class
Trophic Hormones & Related Synthetic Drugs / Cancer Hormone Therapy
ATC Classification
L02AE04 - triptorelin ; Belongs to the class of gonadotropin releasing hormone analogues. Used in endocrine therapy.
Decapeptyl inj 0.1 mg
7 × 1's
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