Avoid use w/ occlusive dressing. Desonide foam is flammable, do not smoke during or immediately after application.
Monitor for hypothalamic-pituitary-adrenal (HPA) axis suppression thru ACTH stimulation test, plasma cortisol test and urinary free cortisol test; signs and symptoms of bacterial or fungal infection.
Enhanced effect w/ other topical corticosteroids.
Description: Desonide is a synthetic corticosteroid that induces phospholipase A2 inhibitory proteins (lipocortins) and sequentially inhibits release of arachidonic acid, hence depresses the formation, release, and activity of chemical inflammatory mediators. Pharmacokinetics: Absorption: Absorbed through normal skin; increased percutaneous absorption in traumatised or inflamed skin. Metabolism: Metabolised in the liver. Excretion: Mainly via urine; bile.
D07AB08 - desonide ; Belongs to the class of moderately potent (group II) corticosteroids. Used in the treatment of dermatological diseases.
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