Doxorubicin - intravesical

Patient Medicine Information
Why do I need this medicine?
Doxorubicin is used on its own or together with other medicines to treat bladder cancer.

This medicine may also be used to treat other conditions as decided by your doctor.
How do I use this medicine?
Doxorubicin is given intravesically (delivered directly into the bladder) via a catheter.

Your doctor or nurse will administer this medicine to you.

Before starting treatment, you may be given other medicines to prevent or lessen the side effects of Doxorubicin. These medicines may be given as tablets or as injections.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the severity of your condition.
What should I do if I have forgotten to use this medicine?
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Doxorubicin.

If you miss an appointment, alert your doctor or nurse. A replacement appointment should be given as soon as possible.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • tumours that have penetrated the bladder wall
  • inflammation of the bladder
  • bladder infection
  • blood in the urine
  • conditions causing difficulty in introduction of the catheter into the bladder
as Doxorubicin may not be suitable for you.

Alert your doctor if you are pregnant or breastfeeding. Do not use this medicine if you are pregnant or planning to have a baby soon. If you become pregnant while on Doxorubicin, alert your doctor immediately. This medicine may cause harm to your unborn child. Both men and women must use proven birth control methods while being treated with Doxorubicin. You may wish to discuss birth control methods with your doctor.
What should I take note of while using this medicine?
Inform your doctor if you have severe renal disease.

Inform your doctor if you have been recently vaccinated. Do not receive any vaccinations without first asking your doctor.

For as long as you are using Doxorubicin, you may need to have routine tests such as urine cytology (test to look for abnormal cells in your urine), blood count, and bladder examination. Your doctor will advise you about how often you need to have these tests. Keep your appointments with your doctor.
What side effects could I experience?
Doxorubicin may cause any of the following side effects: incontinence, slow urination, painful or difficult urination, frequent urination especially at night, and blood in the urine.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • stinging or burning sensation, blisters or skin sores at injection site
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Inform your doctor or pharmacist if you are taking other medicines to treat cancer e.g. cyclophosphamide, dacarbazine, fluorouracil, mitomycin C, trastuzumab.

This list does not include all medicines that may interact with Doxorubicin.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
As the storage temperatures are product specific, please check with your doctor or pharmacist on how it should be stored.

Store Doxorubicin in its original carton to protect from light.

Keep away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on doxorubicin - intravesical and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by
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