Zuellig Pharma
Concise Prescribing Info
Constipation. Soft stool production (eg, haemorrhoids or after colon/anal surgery). Portal systemic encephalopathy (PSE).
Dosage/Direction for Use
Constipation or for stool softening Adult Initially 10-45 mL, maintenance dose: 10-25 mL. Childn 7-14 yr Initially 15 mL, maintenance dose: 10-15 mL, 1-6 yr Initial & maintenance dose: 5-10 mL. Infant <1 yr Initial & maintenance dose: Up to 5 mL. PSE Adult Initially 30-50 mL tds, may adjust to the maintenance dose to achieve 2-3 soft stools/day.
May be taken with or without food: For constipation & the production of soft stools: Preferably taken once at the same time each day. Oral solution may be taken diluted or undiluted. Do not hold the solution in the mouth for any length of time. Ensure adequate fluid intake daily.
Hypersensitivity. Galactosaemia. GI obstruction, digestive perforation or risk of digestive perforation.
Special Precautions
Consult a physician if the desired results are not observed after several days of treatment. Patients experiencing painful abdominal symptoms of unknown cause; serious side effects. Patients w/ hereditary problems of galactose or fructose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Diabetics (when using high doses for PSE). Long-term use of unadjusted doses/misuse can lead to diarrhoea & electrolyte balance disturbance. Discontinue treatment until symptoms have subsided in patients (taking high doses) experiencing diarrhoea &/or abdominal pain.
Adverse Reactions
Diarrhoea, flatulence, abdominal pain, nausea, vomiting, electrolyte imbalance (due to diarrhoea). Hypersensitivity, rash, pruritus, urticaria, erythema.
MIMS Class
Laxatives, Purgatives / Cholagogues, Cholelitholytics & Hepatic Protectors
ATC Classification
A06AD11 - lactulose ; Belongs to the class of osmotically acting laxatives.
Duphalac oral soln 67%
1000 mL x 1's;200 mL x 1's
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