Patient Medicine Information
Why do I need this medicine?
Eplerenone is used to treat high blood pressure.

Eplerenone is also used to treat heart failure in patients who have had a heart attack.
How do I take this medicine?
Take Eplerenone exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

You may take Eplerenone with or without food. Try to take it at the same time each day.

Eplerenone must be taken regularly for it to work well. Continue taking Eplerenone even when you feel better. Do not stop taking it unless instructed by your doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have:

- high potassium levels
- been prescribed with other types of "water pills" such as spironolactone or potassium supplements
as Eplerenone may not be suitable for you.

Do not take Eplerenone together with certain antibiotics and medicines to treat fungal infection, HIV infection, and depression. Please see the section “Can I take this with other medicines?” below for more information.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:

- diabetes
- liver disease
- kidney disease

Let your doctor know if you are pregnant or breastfeeding.

If you are going for an operation, including minor surgery and dental work, inform your doctor or dentist that you are taking Eplerenone.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to Eplerenone regularly. He may also need to do routine blood tests while you are being treated with Eplerenone.

What lifestyle changes can I make to improve my blood pressure?

Regular exercise and eating a healthy diet will help lower your blood pressure and improve your overall health. Engage in physical activity (e.g. walking) at least 30 to 60 minutes on most days of the week. If you have not exercised for a long time, start with light exercises such as slow walks. Speak to your doctor about what type of exercise would be suitable for you. Follow a healthy diet plan by eating more fruits, vegetables, whole grains and low-fat dairy products and reduce your intake of foods high in saturated fat, cholesterol and sodium. Cutting down on deep-fried foods and using less salt when cooking can kick-start your healthy diet.

If you smoke, you should try to quit. Smoking is harmful to your blood pressure, heart and overall health. Speak to your doctor or pharmacist about ways to kick your smoking habit.
What side effects could I experience?
Eplerenone may cause dizziness and tiredness. If affected, do not drive or take part in any activity in which you need to be alert. You may feel dizzy when getting up from a sitting or lying down position, especially if you are taking Eplerenone for the first time. This is normal and should go away as you get used to the medicine. It will help if you get up slowly.

Eplerenone may also cause any of the following side effects: nausea, diarrhoea, muscle spasm or pain, cough and flu-like symptoms.

Other side effects may be serious, although they are not common. Alert your doctor quickly if you experience:

- chest pain
- fast or irregular heartbeat
- muscle weakness, cramping or numbness

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Do not take Eplerenone with the following medicines:

- medicines to treat fungal infection e.g. itraconazole, ketoconazole
- antibiotics e.g. clarithromycin, telithromycin
- medicines for HIV infection e.g. nelfinavir, ritonavir
- nefazodone (medicine to treat depression)

Inform your doctor and pharmacist if you are taking any of these medicines:

- other similar types of medicine e.g. spironolactone, triamterene, amiloride
- medicines for heart disease or high blood pressure e.g. captopril, digoxin, losartan, amiodarone, diltiazem
- NSAIDs (medicines for pain and inflammation) e.g. ibuprofen
- medicines for epilepsy (fits) e.g. phenytoin, carbamazepine
- lithium (medicine for mood)
- ciclosporin (medicine used in organ transplant or certain immune disorders)
- other medicines such as terazosin, trimethoprim, rifampicin

This list does not include all medicines that may interact with Eplerenone.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Do not take potassium supplements. Avoid taking large portions of food that is high in potassium, such as orange juice, bananas or prunes. Do not use salt substitutes that contain potassium.

Avoid grapefruit juice.

Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on eplerenone-oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
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