fusidic acid


Wooridul Life Sciences


Full Prescribing Info
Sodium fusidate.
Sodium fusidate, an antibiotic derived from Fusidium coccineum, exerts powerful antibacterial activity against a number of gram-positive organisms. Staphylococci, including the strains resistant to penicillin or to other antibiotics, are particularly susceptible to sodium fusidate.
The therapeutic efficacy of topically applied Forsuderm ointment is due partly to its pronounced antibacterial activity against the organisms responsible for skin infections, and partly to its ability to penetrate intact skin.
Antibacterial Activity: Staphylococci, Streptococci, Corynebacteria, Clostridia spp.
Application: Effective: Pyoderma (impetigo, infective eczematic dermatitis, folliculitis, furuncle, suppurative hidradenitis, impetiginous eczema), burn, trauma.
Possibly Effective: Acne (acne vulgaris), suture wound, secondary infections after skin grafting.
Dosage/Direction for Use
Adult and children: Clean affected area and apply directly to the wound for several times a day or cover the region with a gauze dressing. Application to a thick layer should be avoided and duration of application is limited to usually 1 week.
History of hypersensitivity to fusidic acid or its salt.
Patients with infection of nonsusceptible organism (especially Pseudomonas aeruginosa).
Special Precautions
Apply to skin only for necessary period because bacterial resistance by Forsuderm may occur.
There is some possibility that sensitization from Forsuderm may occur. If these symptoms eg, itching, rash, swelling, comedo or vesiculosa, occur, discontinue use.
Because Forsuderm has high penetration property, do not apply for long periods or on broad region of the skin.
Appearance of bacterial resistance by topical use may affect the systemic use of this antibiotic. But in general, this resistant bacteria may be susceptible to Forsuderm again in a short time.
Use in children: Since premature infant and neonate have premature liver function, long-term and wide application may result in hepatic disorder.
Use In Pregnancy & Lactation
Use in pregnancy: There are reports to suggest that when given systemically Forsuderm can penetrate the placental barrier. The use of topical application in pregnancy requires that potential benefits should be outweighed against the possible hazards to the fetus.
Use in lactation: Use in lactating mothers with breast infection may result in absorption to infants.
Safety in nursing mothers has not been established. When Forsuderm has been given systemically, levels has been detected in breast milk but with topical use the possible amount of Forsuderm present is unlikely to affect the infant.
Adverse Reactions
Occasionally hypersensitivity reactions eg, skin rashes, weak pain and irritation may occur. If these symptoms occur, discontinue Forsuderm.
Caution For Usage
Application to eye or eyelid is not recommended.
Store in tight containers below 30°C.
MIMS Class
ATC Classification
D06AX01 - fusidic acid ; Belongs to the class of other topical antibiotics used in the treatment of dermatological diseases.
Oint 20 mg/g (white to colorless) x 5 g.
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