Gentamicin sulphate is a broad spectrum aminoglycosides antibiotic which is bactericidal. It acts directly on the bacterial ribosome, where they inhibit protein synthesis and decrease the fidelity of translation of the genetic code. It is effective against many strains of gram-negative bacteria and staphylococcus aureus.
Pharmacology: Gentamicin sulphate is a bactericidal antibiotic which is active against a wide variety of pathogenic gram-positive and gram-negative bacteria. When applied topically to large areas of denuded body surface as the case of burn patients, plasma concentrations can reach 1 mcg/ml, and 2% to 5% of the drug used may appear in the urine.