Human normal immunoglobulin are medicines which contain antibodies (proteins that are normally found in your blood which helps your body to fight infections).
It is used for those who have weak immune system, and to those who do not have enough antibodies in their blood and tend to get frequent infections.
This medicine is used to treat certain types of diseases by correcting the lack of antibodies in your blood. It helps raise abnormally low immunoglobulin levels in your blood to its normal level (replacement therapy).
Human normal immunoglobulin may also be used as antibody replacement therapy for those with cancer of the blood or bone marrow, low antibody before or after transplants.
This medicine may be used to treat other conditions as decided by your doctor.
Your doctor or nurse will administer the injection for you. If you or your caregiver had been given the proper training on the preparation and injection techniques of this medicine, you or your caregiver may do the administration.
Use this medicine exactly as directed by your doctor or according to the instructions on the label. Do not use more or less than instructed by your doctor.
Human normal immunoglobulin is to be injected subcutaneously (into the fatty layer under the skin, usually in the thigh, upper arm or abdomen area).
Remember to rotate the injection sites. Do not inject into the same area all the time. New injection sites should be at least 1.5 inches away from the previous injection site. Do not inject within a 1 inch radius of the navel (belly button) or near infected or inflamed areas.
Do not use Human normal immunoglobulin injection straight from the refrigerator. Allow the injection to reach room temperature before using. This will minimise the pain and discomfort experienced during the injection.
This medicine is available as a vial and a single-use prefilled syringe. Make sure you know how to use the device you have been given. If you have problems or do not understand the instructions, ask your doctor or pharmacist.
The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type and severity of your condition.
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Human normal immunoglobulin.
If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
For home administration, administer the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.
DO NOT double a dose under any circumstances.
If you or your caregiver often forget to administer your medicine, let your doctor and pharmacist know.
Alert your doctor if you have a deficiency of immunoglobulin A (IgA) as Human normal immunoglobulin may not be suitable for you.
Inform your doctor if you have the following conditions:
- over weight
- low blood volume
- blood vessel disease
- blood clotting disorders
- high blood pressure
- kidney disease
- heart disease
Let your doctor know if you are pregnant or breastfeeding.
Use Human normal immunoglobulin with care to an elderly. Elderly may be more sensitive to the side effects of this medicine.
While you are being treated with this medicine, ensure adequate fluid intake to avoid dehydration.
Let your doctor know if you have been recently vaccinated. Do not receive any vaccinations without first asking your doctor.
If you are going for certain laboratory or diagnostic tests, inform your doctor that you are using this medicine.
For as long as you are using this medicine, you may need to have routine blood tests to check your body’s response to the medicine. Your doctor will advise you about how often need to have these tests.
Human normal immunoglobulin may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.
Other side effects include any of the following: injection site redness, itching, swelling or pain, tiredness, headaches, fever, chills, nausea, vomiting, joint and back pain.
Some side effects may be serious, although they are not common. Alert your doctor quickly if you experience:
- rashes, breathlessness, swollen mouth or eyes
- shortness of breath, chest pain
- pain and swelling in the arms or legs
- difficulty or inability to pass urine
- severe headache, stiff neck, sensitivity to light
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Alert your doctor if you have been recently vaccinated. Do not use Human normal immunoglobulin if you had just been vaccinated.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
Store in the refrigerator, between 2-8°C, away from the reach of children. Do not allow to freeze. If frozen, this medicine will become ineffective and should not be used.
Do not use this medicine if it becomes cloudy or if it has changed in colour.
Do not shake this medicine.
The container should be replaced in the outer carton after use to protect the contents from light.
Medicines must not be used past the expiry date.