Medical supervision is indicated in patients with chronic rhinitis. Should only be used after consultation with a physician during pregnancy and lactation. The recommended dosage must not be exceeded. No impairment on ability to drive and use machineries is to be expected if used as recommended. Systemic effects with CV involvement cannot be excluded after prolonged administration or intake of oxymetazoline-containing cold remedies in doses higher than recommended. In these cases, the ability to drive a vehicle or operate machinery can be impaired.