Indometacin - oral

Patient Medicine Information
Why do I need this medicine?
Indometacin helps relieve pain and inflammation. It is used to reduce swelling to provide pain relief associated with joint disorder.

This medicine may also be used to treat fever and pain due to menstrual period or surgery.

Indometacin may be used to treat other conditions as decided by your doctor.
How do I take this medicine?
Take Indometacin exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take this medicine together with food or immediately after a meal. Do not take it on an empty stomach.

To avoid stomach discomfort, your doctor may also prescribe some antacid (medicines to neutralise stomach acid) tablets to be taken with Indometacin. If you have been given an antacid, take it together with Indometacin.

If you have been given the extended-release capsule (usually labelled as “ER”), swallow it whole. Do not divide, chew or crush it.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Do not take Indometacin if you ever had an allergic reaction (rashes, breathlessness, swollen eyes) to similar medicines such as aspirin, mefenamic acid, ibuprofen, ketoprofen, meloxicam, naproxen or piroxicam.

This medicine should not be used to treat pain in the setting of coronary artery bypass graft surgery (procedure to improve and restore the blood flow in the heart).
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:

- have or had a history of stomach ulcer or bleeding
- bleeding or blood clot disorder
- heart disease
- high blood pressure
- kidney disease
- liver disease
- epilepsy (fits or seizures)
- mental illnesses
- Parkinson’s disease (disorder that affects movement of a person, causing symptoms such as tremors, muscle stiffness, slowed movement and impaired balance or walking)

Let your doctor know if you are pregnant or breastfeeding.

If you are going for an operation, including minor surgery and dental work, inform your doctor or dentist that you are taking Indometacin.

For as long as you are taking Indometacin, you may need to have regular blood tests, liver and kidney function tests to check your body’s response to the medicine. Your doctor will advise you about how often you need to have these tests. Pain response, inflammation, blood pressure, bleeding or bruising should also be monitored.
What side effects could I experience?
Indometacin may cause dizziness, drowsiness or blurred vision. If affected, do not drive or take part in any activity in which you need to be alert or need to see clearly.

Other side effects include any of the following: headache, nausea, vomiting, diarrhoea, constipation, indigestion, stomach pain and tiredness.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:

- difficulty breathing
- swelling of the face, lips, tongue or throat
- rashes
- pass blood or black tarry stool

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:

- blood-thinning medicines e.g. aspirin, warfarin
- medicines for the heart and high blood pressure e.g. digoxin, atenolol, propranolol, losartan
- diuretics or “water pills” e.g. furosemide
- medicines used in organ transplant or certain immune disorders e.g. ciclosporin
- medicines used to treat cancer e.g. methotrexate
- medicines for depression e.g. lithium
- medicines for gout e.g. probenecid
- medicines for pain, inflammation or fever e.g. diflunisal

This list does not include all medicines that may interact with Indometacin.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on indometacin - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by
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