Iopamiro 370

Iopamiro 370





DCH Auriga
Concise Prescribing Info
Iopamidol 37.76 g/50 mL or 75.53 g/100 mL (iodine 370 mg/mL)
Radiographic procedures including neuroradiology (myeloradiculography, cisternography & ventriculography), angiography [cerebral, coronary, selective visceral & peripheral arteriography; angiocardiography; thoracic & abdominal aortography; venography; digital subtraction angiography (DSA), DSA of cerebral or peripheral or abdominal arteries], urography (IV urography), arthrography & fistulography. Contrast enhancement in computed tomography (CT) scanning.
Dosage/Direction for Use
Myeloradiculography, cisternography & ventriculography 5-15 mL of 300 mg iodine/mL. Cerebral arteriography 5-10 mL (bolus) of 300 mg iodine/mL. Coronary arteriography 8-15 mL (bolus) of 370 mg iodine/mL. Angiocardiography, thoracic & abdominal aortography 1-1.2 mL/kg of 370 mg iodine/mL. Selective visceral arteriography Depending on exam (300-370 mg iodine/mL). Peripheral arteriography 40-50 mL of 300-370 mg iodine/mL. DSA Depending on exam (150-370 mg iodine/mL). Venography 30-50 mL of 300 mg iodine/mL. Urography 30-50 mL of 300-370 mg iodine/mL. Contrast enhancement in CT scanning 0.5-2 mL/kg of 300-370 mg iodine/mL. Arthrography, fistulography Depending on exam (300 mg iodine/mL).
Waldenstrom's macroglobulinemia, multiple myeloma; severe liver & kidney diseases.
Special Precautions
Never mix other drugs w/ contrast medium soln. Do not limit fluid intake before administering a hypertonic contrast soln when examining small childn or babies. Hyperthyroidism. Hypothyroidism. Pregnancy. Infants especially preterm. Neuroradiology: May be contraindicated in patients w/ history of epilepsy; presence of blood in CSF. Discontinue drugs that lower the seizure threshold (eg, neuroleptics & analgesics, antiemetics, antihistamine & sedatives of the phenothiazine group) at least 48 hr before administration & not to be resumed <12 hr after procedure completion. Angiography: Advanced arteriosclerosis, HTN, heart failure, major systemic diseases & recent cerebral embolism or thrombosis. Monitor for right heart insufficiency & pulmonary HTN. Inj into right heart chambers of cyanotic neonates w/ pulmonary HTN & impaired cardiac function. Carefully position the tip of catheter during aortic arch exam & abdominal aortography.
Adverse Reactions
Risk of anaphylaxis, skin & severe CV reactions. Dizziness, neck rigidity, lumbar or sciatic pain. Neuroradiology: Headache, nausea, vomiting & inj site pain; fever; muscular spasms or generalized convulsions. Angiography: Heat sensation in face & neck, headache, bradycardia w/ systemic hypotension, severe neurological sequelae. Arthrography/fistulography: Irritative manifestations superimposed on existing tissue inflammation.
Drug Interactions
Neuroradiology: Neuroleptics. Analgesics, antiemetics, antihistamines & sedatives of the phenothiazine group.
ATC Classification
V08AB04 - iopamidol ; Belongs to the class of watersoluble, nephrotropic, low osmolar preparations used as X-ray contrast media.
Iopamiro inj iopamidol 370 mg iodine/50 mL
50 mL x 1's
Iopamiro inj iopamidol 370 mg iodine/100 mL
100 mL x 1's
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