Janumet Contraindications

metformin + sitagliptin




Zuellig Pharma
Full Prescribing Info
History of a serious hypersensitivity reaction to Janumet or sitagliptin eg, anaphylaxis or angioedema. (See Precautions and Adverse Reactions.)
Patients with renal disease or renal dysfunction eg, as suggested by serum creatinine levels ≥1.5 mg/dL (males), ≥1.4 mg/dL (females) or abnormal creatinine clearance which may also result from conditions eg, cardiovascular collapse (shock), acute myocardial infarction and septicemia (see Precautions).
Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma.
Janumet should be temporarily discontinued in patients undergoing radiologic studies involving intravascular administration of iodinated contrast materials, because use of such products may result in acute alteration of renal function (see Precautions).
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