Ketorolac - Nasal

Patient Medicine Information
Why do I need this medicine?
Ketorolac is used to help relieve moderate to severe pain.
How do I use this medicine?
Use Ketorolac nasal spray exactly as directed by your doctor or according to the instructions on the label. Do not use more or less than instructed by your doctor.

How to use:
  1. If you are using the nasal spray for the first time, activate the pump. To activate the pump, hold the bottle at arm’s length away you. Place your index finger and middle finger on the top of the flange, while supporting the bottom with your thumb. Press down evenly and release pump 5 times. There is no need to activate the pump again if more doses are used from the bottle.
  2. Blow your nose gently to clear nostrils.
  3. Sit up straight or stand. Tilt head slightly forward.
  4. Insert the tip of the container into your right nostril.
  5. Hold the bottle upright and aim the tip towards the back of your nose.
  6. Hold your breath and spray 1 time into your right nostril, pressing down on both sides of the finger flange. Pinch your nose to help keep the medicine in your nose.
  7. Breathe in gently through your mouth.
  8. Repeat procedures 3-7 on your left nostril if your doctor advised you to do so.
  9. Wipe and cap the nasal spray after using.
Make sure you know how to use your nasal spray. If you have problems or do not understand the instructions, ask your doctor or pharmacist.

Do not use Ketorolac nasal spray for more than 5 days. This medicine is indicated only as a short-term pain relief therapy. Your doctor will advise you on the dose and duration of your treatment.
What should I do if I have forgotten to use this medicine?
Use the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.
When should I not use this medicine?
Do not use this medicine if you ever had an allergic reaction (rashes, breathlessness, swollen eyes, asthma) to Ketorolac or other similar medicines for pain and inflammation such as non-steroidal anti-inflammatory drugs (NSAIDs) or aspirin.

Alert your doctor if you have the following conditions:
  • active or history of stomach ulcer or bleeding
  • bleeding disorders or at high risk of bleeding
  • at risk for kidney failure due to dehydration
as Ketorolac may not be suitable for you.

Do not use this medicine if you are on your 3rd trimester of pregnancy.

This medicine should not be used to treat pain in the setting of coronary artery bypass graft surgery (procedure to improve and restore the blood flow in the heart), labour, and delivery, or for the prevention of pain before major surgery.

Do not use this medicine with other painkillers, or medicines used to treat gout or circulation problems. Please see the section “Can I use this with other medicines?” below for more information.
What should I take note of while using this medicine?
Inform your doctor if you have the following conditions:
  • bowel inflammation e.g. ulcerative colitis (inflammation of the large intestines), Crohn’s disease (long-term inflammatory disease of the digestive tract)
  • recent stroke, heart attack or heart failure
  • bleeding disorder
  • kidney disease
  • liver disease
  • high blood pressure
  • diabetes
  • asthma
  • low volume of circulating blood in the body
  • low body weight (<50 kg)
Let your doctor know if you are pregnant or breastfeeding.

Notify your doctor if you consume alcohol or if you are a smoker.

Be sure to check with your doctor or pharmacist before giving Ketorolac to an elderly or those who are debilitated (a person who is physically or mentally weak usually due to illness or old age). Elderly and debilitated people may be more sensitive to the side effects.

If you are going for an operation, including minor surgery and dental work, inform your doctor or dentist that you are using this medicine.

For as long as you are using this medicine, you may need to have regular blood tests, liver and kidney function tests to check your body’s response to the medicine. Your doctor will advise you about how often you will need to have these tests.
What side effects could I experience?
Ketorolac may cause any of the following side effects: nasal discomfort, pain or irritation, throat irritation, and watery eyes.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • pass out blood or black, tarry stools or vomit coffee-ground-like vomitus
  • yellowing of the skin or eyes, severe persistent stomach pain, dark coloured urine, unusual tiredness
  • rashes with peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
  • chest pain
If you develop rashes, breathlessness, swollen mouth or eyes, stop using this medicine and inform your doctor immediately. These could be signs of an allergic reaction.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Do not use Ketorolac if you are taking any of these medicines:
  • other medicines for pain and inflammation e.g. NSAIDs, aspirin
  • medicine for gout e.g. probenecid
  • medicine used to improve blood flow e.g. pentoxifylline
Inform your doctor and pharmacist if you are taking or using any of these medicines:
  • medicines for high blood pressure or heart disease e.g. captopril, losartan, digoxin
  • medicines for water retention (water pills) e.g. furosemide, hydrochlorothiazide, spironolactone
  • medicines for epilepsy (fits or seizures) e.g. phenytoin, carbamazepine
  • medicines for mood disorder e.g. lithium, fluoxetine, thiothixene
  • medicine for anxiety e.g. alprazolam
  • blood-thinning medicines e.g. warfarin
  • methotrexate (medicine used to treat certain types of cancer)
This list does not include all medicines that may interact with Ketorolac.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
If the nasal spray has not yet been opened, store it in the refrigerator, between 2-8°C. Do not freeze, otherwise this medicine will become ineffective and should not be used.

Once it is opened, store the bottle in an upright position in a cool, dry place away from the reach of children.

Protect from light.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on Ketorolac - Nasal and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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