Ketorolac - oral

Patient Medicine Information
Why do I need this medicine?
Ketorolac is used to help relieve moderate to severe pain that may occur after a surgery.
How do I take this medicine?
Take Ketorolac exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take it together with food or immediately after a meal.

This medicine is a short-term pain relief therapy that is only indicated as a continuation following a Ketorolac treatment that is given either intravenously (into the vein) or intramuscularly (into the muscle). Your doctor will advise you on the dose and duration of your treatment.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.
When should I not use this medicine?
Do not take this medicine if you ever had an allergic reaction (rashes, breathlessness, swollen eyes, asthma) to Ketorolac or other similar medicines for pain and inflammation such as non-steroidal anti-inflammatory drugs (NSAIDs) or aspirin.

Alert your doctor if you have the following conditions:
  • active or history of stomach ulcer or bleeding
  • bleeding disorders or at high risk of bleeding
  • severe heart disease
  • moderate to severe kidney disease
  • at risk for kidney failure due to dehydration
  • severe liver disease
as Ketorolac may not be suitable for you.

Do not take this medicine if you are on your 3rd trimester of pregnancy.

This medicine should not be used to treat pain in the setting of coronary artery bypass graft surgery (procedure to improve and restore the blood flow in the heart), labour, and delivery, or for the prevention of pain before major surgery.

Do not take this medicine with other painkillers, or medicines used to treat gout or circulation problems. Please see the section “Can I take this with other medicines?” below for more information.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • bowel inflammation e.g. ulcerative colitis (inflammation of the large intestines), Crohn’s disease (long-term inflammatory disease of the digestive tract)
  • recent stroke, heart attack or heart failure
  • bleeding disorder
  • lupus or systemic lupus erythematosus (autoimmune disease that causes inflammation)
  • mild kidney disease
  • mild to moderate liver disease
  • high blood pressure
  • diabetes
  • asthma
  • low volume of circulating blood in the body
  • low body weight (<50 kg)
Let your doctor know if you are pregnant or breastfeeding.

Notify your doctor if you consume alcohol or if you are a smoker.

Be sure to check with your doctor or pharmacist before giving Ketorolac to an elderly or those who are debilitated (a person who is physically or mentally weak usually due to illness or old age). Elderly and debilitated people may be more sensitive to the side effects.

If you are going for an operation, including minor surgery and dental work, inform your doctor or dentist that you are taking this medicine.

For as long as you are taking this medicine, you may need to have regular blood tests, liver and kidney function tests to check your body’s response to the medicine. Your doctor will advise you about how often you will need to have these tests.
What side effects could I experience?
Ketorolac may cause drowsiness, dizziness or blurred vision. If affected, do not drive or take part in any activity in which you need to be alert or need to see clearly.

Other side effects include any of the following: headache, nausea, vomiting, indigestion, stomach pain, constipation, diarrhoea, stomach wind, and heartburn (burning pain in your chest caused by food or acid from your stomach that backs up into your mouth).

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • rashes with peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
  • pass out blood or black, tarry stools or vomit coffee-ground-like vomitus
  • unusual bleeding or bruising
  • yellowing of the skin or eyes, severe persistent stomach pain, dark coloured urine, unusual tiredness
  • chest pain
If you develop rashes, breathlessness, swollen mouth or eyes, stop taking this medicine and inform your doctor immediately. These could be signs of an allergic reaction.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Do not take Ketorolac if you are taking any of these medicines:
  • other medicines for pain and inflammation e.g. NSAIDs, aspirin
  • medicine for gout e.g. probenecid
  • medicine used to improve blood flow e.g. pentoxifylline
Inform your doctor and pharmacist if you are taking or using any of these medicines:
  • medicines for high blood pressure or heart disease e.g. captopril, losartan, digoxin
  • medicines for water retention (water pills) e.g. furosemide, hydrochlorothiazide, spironolactone
  • medicines for epilepsy (fits or seizures) e.g. phenytoin, carbamazepine
  • medicines for mood disorder e.g. lithium, fluoxetine, thiothixene
  • medicine for anxiety e.g. alprazolam
  • blood-thinning medicines e.g. warfarin
  • medicines used in organ transplant or certain immune disorders e.g. tacrolimus, ciclosporin
  • methotrexate (medicine used to treat certain types of cancer)
This list does not include all medicines that may interact with Ketorolac.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on ketorolac - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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