Magnesium hydroxide

Generic Medicine Info
Indications and Dosage
Gastrointestinal hyperacidity
Adult: Up to 1 g daily, usually given in conjunction with an aluminium-containing antacid eg, aluminium hydroxide.

Osmotic laxative
Adult: 2.4-4.8 g daily as a single dose or in divided doses.
Child: 6-11 yr: 1.2-2.4 g daily; 2-5 yr: 0.4-1.2 g daily. Doses may be given as a single dose or in divided doses.
Intestinal obstruction, faecal impaction; renal failure; appendicitis.
Special Precautions
Colostomy, ileostomy; electrolyte imbalance. Monitor for toxicity in patients with impaired renal function. Pregnancy.
Adverse Reactions
GI irritation, diarrhoea, abdominal cramps; hypermagnesaemia (in patients with renal impairment). Paralytic ileus.
Drug Interactions
Decreases absorption of tetracyclines and biphosphonates. Separate administration of these and other drugs by around 2 hr.
Description: Magnesium hydroxide increases peristaltic activity causing osmotic retention of fluids, thus resulting in bowel evacuation. It also reduces stomach acid by reacting with hydrochloric acid to form Mg chloride.
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