Mefloquine - oral

Patient Medicine Information
Why do I need this medicine?
Mefloquine is used for the treatment and prevention of malaria.
How do I take this medicine?
Take Mefloquine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

This medicine should be taken with food or immediately after a meal with a full glass of water to minimise stomach discomfort.

If you have difficulty swallowing tablet(s), you may dissolve the tablet(s) in a glass of water, milk or other liquid beverages, stir and drink immediately. This may also help to mask its bitter taste.

Take Mefloquine at regular intervals for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.

Do not skip any doses. You must complete the entire course of this medicine. If you don't, the infection will not clear completely.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Do not take Mefloquine if you have a history of allergic reactions (rashes, breathlessness, swollen eyes) to similar medicines such as quinine and quinidine.

Alert your doctor if you have the following conditions:

- mental illness e.g. depression, suicidal attempts, schizophrenia
- severe liver disease
- epilepsy (fits or seizures)
as Mefloquine may not be suitable for you.

DO NOT take Mefloquine together with halofantrine (a medicine to treat malaria).
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:

- liver disease
- kidney disease
- heart disease

Let your doctor know if you are pregnant or breastfeeding.

For as long as you are taking this medicine, you may need to have regular blood tests to check your body's response to the medicine. You may also need regular eye check-ups to ensure that Mefloquine does not cause any eye problems. Your doctor will advise you about how often you need to have these tests.
What side effects could I experience?
Mefloquine may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: fever, nausea, vomiting, diarrhoea, stomach discomfort, loss of appetite, headache, tiredness, muscle pain, and rashes.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience mood disturbances such as depression, anxiety or confusion.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:

- medicines for epilepsy (fits or seizures) e.g. carbamazepine, phenobarbital, phenytoin
- medicines for mood disorders e.g. valproate
- other medicines to treat malaria e.g. chloroquine, quinine
- medicines for heart disease e.g. quinidine, amiodarone
- antibiotics e.g. ampicillin, rifampicin, ciprofloxacin
- medicines to treat fungal infections e.g. ketoconazole

This list does not include all medicines that may interact with Mefloquine.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on mefloquine - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by
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