Mefloquine is used for the treatment and prevention of malaria.
Take Mefloquine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
This medicine should be taken with food or immediately after a meal with a full glass of water to minimise stomach discomfort.
If you have difficulty swallowing tablet(s), you may dissolve the tablet(s) in a glass of water, milk or other liquid beverages, stir and drink immediately. This may also help to mask its bitter taste.
Take Mefloquine at regular intervals for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
Do not skip any doses. You must complete the entire course of this medicine. If you don't, the infection will not clear completely.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.
DO NOT double a dose under any circumstances.
If you often forget to take your medicine, let your doctor and pharmacist know.
Do not take Mefloquine if you have a history of allergic reactions (rashes, breathlessness, swollen eyes) to similar medicines such as quinine and quinidine.
Alert your doctor if you have the following conditions:
- mental illness e.g. depression, suicidal attempts, schizophrenia
- severe liver disease
- epilepsy (fits or seizures)
as Mefloquine may not be suitable for you.
DO NOT take Mefloquine together with halofantrine (a medicine to treat malaria).
Inform your doctor if you have the following conditions:
- liver disease
- kidney disease
- heart disease
Let your doctor know if you are pregnant or breastfeeding.
For as long as you are taking this medicine, you may need to have regular blood tests to check your body's response to the medicine. You may also need regular eye check-ups to ensure that Mefloquine does not cause any eye problems. Your doctor will advise you about how often you need to have these tests.
Mefloquine may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.
Other side effects include any of the following: fever, nausea, vomiting, diarrhoea, stomach discomfort, loss of appetite, headache, tiredness, muscle pain, and rashes.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience mood disturbances such as depression, anxiety or confusion.
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Inform your doctor and pharmacist if you are taking any of these medicines:
- medicines for epilepsy (fits or seizures) e.g. carbamazepine, phenobarbital, phenytoin
- medicines for mood disorders e.g. valproate
- other medicines to treat malaria e.g. chloroquine, quinine
- medicines for heart disease e.g. quinidine, amiodarone
- antibiotics e.g. ampicillin, rifampicin, ciprofloxacin
- medicines to treat fungal infections e.g. ketoconazole
This list does not include all medicines that may interact with Mefloquine.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
Store in a cool, dry place away from the reach of children.
Medicines must not be used past the expiry date.