Cardiovascular System: Oedema, lower limb oedema, elevated blood pressure (see also Precautions), palpitations and flushes.
Central Nervous System: Drowsiness, headache, lightheadedness, tinnitus and vertigo may occur. Rare instances of confusion, insomnia and nightmares.
Dermatological: Reports of skin rash, pruritus, urticaria and photosensitivity reactions. Very rarely, erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis, or other bullous reactions.
Gastrointestinal System: Abdominal pain, constipation, diarrhoea, dyspepsia, flatulence, nausea, oesophagitis, stomatitis and vomiting may occur. Rare instances of peptic ulceration, perforation or gastrointestinal bleeding, sometimes severe, particularly in the elderly (see Precautions). Reports of rare cases of gastritis.
Genitourinary System: Laboratory tests of renal function may be disturbed eg, elevated creatinine or urea.
Haematological System: Reports of blood count disturbances in patients taking meloxicam, some of which have been attributed to therapy; anaemia, leucocytopenia, and thrombocytopenia. There are isolated reports of agranulocytosis in patients taking meloxicam and other drugs with myelotoxic potential.
Hepatic System: Liver function tests may show transitory disturbance eg, elevation of bilirubin or transaminase levels.
Immunological: Rare reports of angioedema and anaphylactic or anaphylactoid reactions.
Pulmonary System: Patients allergic to aspirin or other NSAIDs have experienced asthma attacks.
Sensory System: Rare reports of visual disturbances, including blurred vision.