Mepolizumab - subcutaneous

Patient Medicine Information
Why do I need this medicine?
Mepolizumab is used to treat a rare severe form of asthma caused by high level of white blood cells called eosinophils.

This medicine may also be used to treat other conditions as decided by your doctor.
How do I use this medicine?
Mepolizumab is to be injected subcutaneously (into the fatty layer under the skin, usually in the upper arm, thigh or abdomen area).

Your doctor or nurse will administer the injection for you.

Remember to rotate the injection sites. Do not inject into the same area all the time. If more injection is administered at the same site, separate injections in increments at least 2 inches apart. Do not inject near the navel (belly button).

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the course of your treatment depending on your condition.
What should I do if I have forgotten to use this medicine?
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Mepolizumab.

If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
What should I take note of while using this medicine?
Inform your doctor if you have or living in a region with common parasitic infestation. It should be treated before starting therapy with Mepolizumab.

Your doctor may advise you to receive a vaccination for viral infection if appropriate before initiating treatment with this medicine.

Let your doctor know if you are pregnant or breastfeeding.

Be sure to consult your doctor or pharmacist before giving Mepolizumab to a child.

If you are also taking oral or inhaled steroids, do not stop the steroid unless your doctor has specifically told you to do so. Your doctor will gradually reduce the dose of your steroids. Follow your doctor's instructions carefully.

Your doctor needs to monitor your condition and check your response to the medication regularly.
  • You may need to have routine lung tests (e.g. pulmonary function tests) while you are being treated with Mepolizumab. Your doctor will advise you about how often you will need to have these tests.
  • Regular monitoring may be necessary for signs and symptoms of worsening in your asthma condition.
What side effects could I experience?
Mepolizumab may cause any of the following side effects: headache, stuffy nose, common cold, sore throat, stomach pain, bladder infection, tiredness, muscle pain, itching and burning sensation at the site of injection.

If you develop rashes, breathlessness, light headedness, swollen eyes, face, or mouth, stop taking this medicine and inform your doctor quickly. These could be signs of an allergic reaction.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in the refrigerator, between 2-8°C. Do not allow to freeze. If frozen, this medicine will become ineffective and should not be used.

If you notice that the injection has changed colour or has become cloudy, do not use it. Throw it away and use a new injection.

Keep in the original packaging to protect from light. Keep away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on mepolizumab - subcutaneous and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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