Respiratory depression, head injury, paralytic ileus, biliary colic, delayed gastric emptying, obstructive airways disease, cardiac arrhythmias, known morphine sensitivity, acute hepatic disease, concurrent administration of monoamine oxidase inhibitors (MAOIs) or within 2 weeks of discontinuation of their use (see Interactions).
Should paralytic ileus be suspected or occur during use, MST Continus tablets should be discontinued immediately.
MST Continus tablets are not recommended for paediatric use or in pregnancy.
Preoperative administration of MST Continus tablets is not recommended and is not an approved indication.
Not recommended for preoperative use or for the first 24 hrs postoperatively.
Use in pregnancy & lactation: Use of MST Continus should be avoided during pregnancy and labour due to risk of neonatal respiratory depression. Administration to nursing mothers is not recommended as morphine is excreted in breast milk.
Withdrawal symptoms may be observed in the newborn of mothers undergoing chronic treatment.