Closely supervise patients for 15 min following inj. Patients w/ CV disease; suffering from epilepsy or brain lesions; history of asthma or other allergic disorders. Do not use in patients w/ history of sensitivity to benzyl alcohol. As w/ other other gadolinium-chelates, contrast-enhanced MRI ashould not be performed w/in 7 hr of MultiHance-enhanced MRI exam. Avoid local extravasation during IV administration. Use the lowest effective dose & perform risk assessment before administering repeated doses. Screen patients for renal dysfunction (obtain laboratory tests) prior to administration. Avoid in patients w/ severe renal impairment & peri-op liver transplantation. Pregnancy & lactation. Not recommended in childn <2 yr (brain & spine MRI), <18 yr (liver & breast MRI, MRA). Elderly (≥65 yr).