Neoderm Cream combines the sustained anti-inflammatory, antipruritic and vaso-constrictive actions of betamethasone dipropionate with the broad spectrum antifungal activity of clotrimazole and the wide-spectrum antibiotic activity of gentamicin sulfate. Clotrimazole appears to act on the fungal cell membrane, causing leakage of cell contents. Gentamicin provides highly effective topical treatment in primary and secondary bacterial infections of the skin.