Netupitant + palonosetron - oral

Patient Medicine Information
Why do I need this medicine?
Netupitant and Palonosetron are combined together in this medicine.

Netupitant + Palonosetron is used together with other medicines to prevent nausea and vomiting associated with cancer chemotherapy (cancer treatment).
How do I take this medicine?
Take Netupitant + Palonosetron exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

You may take this medicine with or without food. Take it at least 1 hour before taking your scheduled medication for cancer. Try to take it at the same time each day.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember.

DO NOT double a dose under any circumstances.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • severe liver disease
  • severe kidney disease
as this medicine may not be suitable for you.

Do not take Netupitant + Palonosetron if you are pregnant or planning to have a baby soon. If you become pregnant while being treated with this medicine, alert your doctor immediately. Netupitant + Palonosetron may cause harm to your unborn child. You must use proven birth control methods while taking this medicine.

Do not breastfeed while you are being treated with this medicine.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • history of constipation
  • blocked bowel
  • history of heart disease e.g. irregular heartbeat, heart failure
  • electrolyte imbalance (imbalance of minerals in the body)
Your doctor may need to do liver and kidney function test, as Netupitant + Palonosetron is not indicated to be taken by those with severe liver or kidney disease.
What side effects could I experience?
Netupitant + Palonosetron may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects may include any of the following: constipation, indigestion, headache, weakness, tiredness and skin redness.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • agitation
  • seeing, hearing or feeling things that are not existent
  • dizziness
  • extremely high body temperature
  • tremor
  • nausea
  • vomiting
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines used to treat depression or anxiety e.g. fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, escitalopram, duloxetine, venlafaxine
  • medicines to treat cancer e.g. docetaxel, etoposide
  • certain antibiotics e.g. erythromycin
  • medicines for sleep disorder or anxiety e.g. midazolam
  • steroid used for a variety of condition e.g. dexamethasone
  • medicines used to treat fungal infection e.g. ketoconazole
  • medicines to treat TB (infection known as tuberculosis) e.g. rifampicin
This list does not include all medicines that may interact with Netupitant + Palonosetron.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on netupitant + palonosetron - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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