Oral candidiasis
Adult: In patients with denture sores or oral infections caused by Candida albicans: As susp: 100,000 units 4 times daily, higher doses of 400,000-600,000 units 4 times daily may also be given as necessary. Keep in contact with affected areas for as long as possible before swallowing. Treatment duration: Generally, 7-14 days or continue treatment for at least 48 hours after clinical cure is achieved to prevent relapse.
Child: As susp: Infant: 100,000 units 4 times daily, higher doses of 200,000 units 4 times daily (with ½ of the dose in each side of the mouth) may also be given as necessary. Keep in contact with affected area for as long as possible before feeding. Children: Same as adult dose. For prophylaxis of oral candidiasis in infants born of mothers with vaginal candidiasis: 100,000 units once daily.
Child: As susp: Infant: 100,000 units 4 times daily, higher doses of 200,000 units 4 times daily (with ½ of the dose in each side of the mouth) may also be given as necessary. Keep in contact with affected area for as long as possible before feeding. Children: Same as adult dose. For prophylaxis of oral candidiasis in infants born of mothers with vaginal candidiasis: 100,000 units once daily.
Oral
Intestinal candidiasis
Adult: Treatment: As susp: 500,000 units 4 times daily; swish and retain in the mouth and kept in contact with the affected area for as long as possible before swallowing. As tab/cap: 500,000-1,000,000 units 3 or 4 times daily. Prophylaxis: As susp/tab: 1,000,000 units daily. Continue treatment for at least 48 hours after clinical cure is achieved to prevent relapse.
Child: Infant and children: As susp: 100,000 units into the mouth 4 times daily; swish and retain in the mouth and kept in contact with the affected area for as long as possible before swallowing.
Child: Infant and children: As susp: 100,000 units into the mouth 4 times daily; swish and retain in the mouth and kept in contact with the affected area for as long as possible before swallowing.
Topical/Cutaneous
Cutaneous or mucocutaneous mycotic infections
Adult: As cream/ointment/dusting powder: Apply to the affected area bid or as clinically indicated until healing is complete.
Vaginal
Vulvovaginal candidiasis
Adult: As pessary: 100,000-200,000 units daily preferably at bedtime for 14 consecutive days or longer. As vaginal cream: Apply 100,000 units (1 applicator-full) intravaginally 1 or 2 times daily for 14 days or longer. Continue treatment regardless of intervening menstruation.