The most frequent adverse reactions seen in clinical trials are nausea, headache and vomiting. (See table.)
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The frequencies of the side effects are based on post-marketing experience.
Diarrhoea and faecal incontinence are the primary clinical effect of PICOPREP. Isolated cases of severe diarrhoea have been reported post-marketing.
Hyponatraemia has been reported with or without associated convulsions. In epileptic patients, there have been isolated reports of seizure/grand mal convulsion without associated hyponatraemia.
There have been isolated reports of anaphylactoid reaction.