PMS-Gabapentin

PMS-Gabapentin

gabapentin

Manufacturer:

Pharmascience

Distributor:

Medicell Pharma
Concise Prescribing Info
Contents
Gabapentin
Indications/Uses
Adjunctive therapy for management of partial seizures w/ or w/o secondary generalization in adults w/ epilepsy.
Dosage/Direction for Use
Adult & childn >12 yr 900-1,800 mg/day. Initially 300 mg/day or by dose titration: 300 mg on day 1, 300 mg bd on day 2 & 300 mg tds on day 3. May be increased up to 1,800 mg/day. Max dose interval: 12 hr. Elderly & patients w/ renal impairment CrCl >60 mL/min 1,200 mg/kg daily (400 mg tds); 30-60 mL/min 600 mg/kg daily (300 mg bd); 15-30 mL/min 300 mg/kg daily; <15 mL/min 150 mg/kg daily (300 mg every other day). Hemodialysis Loading dose: 300-400 mg, then 200-300 mg maintenance dose following each 4 hr of hemodialysis.
Administration
May be taken with or without food.
Special Precautions
Not for treatment of absence seizures. Mixed seizure disorders including absence seizures. Avoid abrupt w/drawal of therapy. May impair ability to drive or operate machinery. Pregnancy & lactation. Childn <12 yr.
Adverse Reactions
Somnolence, dizziness, ataxia, fatigue, nystagmus & tremor.
Drug Interactions
Al- & Mg-based antacid, cimetidine.
ATC Classification
N03AX12 - gabapentin ; Belongs to the class of other antiepileptics.
Presentation/Packing
Form
PMS-Gabapentin cap 100 mg
Packing/Price
100's
Form
PMS-Gabapentin cap 300 mg
Packing/Price
100's
Form
PMS-Gabapentin cap 400 mg
Packing/Price
100's
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