PMS-Sodium Polystyrene Sulfonate

PMS-Sodium Polystyrene Sulfonate

sodium polystyrene sulfonate




Medicell Pharma
Concise Prescribing Info
Na polystyrene sulfonate
Treatment of hyperkalaemia.
Dosage/Direction for Use
Adult Oral susp 60 mL once-qds. Powd for susp 15-60 g daily, give each dose as a susp in a small quantity of water or syrup (20-100 mL or 3-4 mL/g of resin). Rectal powd for susp 30-45 g once-bd at 6-hr interval, administer as warm emulsion in 150-120 mL of aqueous vehicle. Enema 120-180 mL as retention enema administered following a cleansing enema.
May be taken with or without food: Suspend powd in a small quantity of water/syr.
Special Precautions
Monitor serum K levels & all applicable electrolyte disturbances. Chronic hypocalcemia of renal failure. Intolerance of slight increase in Na loads ie severe CHF or HTN & marked edema. Elderly.
Adverse Reactions
Gastric irritation, anorexia, nausea, vomiting, constipation, hypokalemia, hypocalcaemia & significant Na retention. Occasionally, diarrhea. Large doses in elderly may cause fecal impaction. Intestinal obstruction when used concomitantly w/ Al(OH)3.
Drug Interactions
Non-absorbable cation-donating antacids & laxatives eg Mg hydroxide & Al carbonate. Diuretics, K-sparing or K supplements.
ATC Classification
V03AE01 - polystyrene sulfonate ; Belongs to the class of drugs used in the treatment of hyperkalemia and hyperphosphatemia.
PMS-Sodium Polystyrene Sulfonate oral susp 15 g/60 mL
500 mL x 1's
PMS-Sodium Polystyrene Sulfonate enema 30 g/120 mL
120 mL x 1's
PMS-Sodium Polystyrene Sulfonate powd for oral susp 94.3 mg/g
454 g x 1's
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