Proxyphylline


Concise Prescribing Info
Contraindications
Porphyria.
Special Precautions
Peptic ulceration, hyperthyroidism, hypertension, cardiac arrhythmias or other CV disease, or epilepsy, heart failure, hepatic dysfunction or chronic alcoholism, acute febrile illness. Neonates and elderly.
Adverse Reactions
Nausea, vomiting, abdominal pain, diarrhoea, gastro-oesophageal reflux and other GI disturbances, insomnia, headache, anxiety, restlessness, dizziness, tremor and palpitations.
Drug Interactions
Concurrent use with other xanthines may cause additive toxic effects. Clearance may be reduced by allopurinol, some antiarrhythmics, cimetidine, disulfiram, fluvoxamine, interferon alfa, macrolide antibacterials and quinolones, oral contraceptives, tiabendazole and viloxazine. Phenytoin and some other antiepileptics, ritonavir, rifampicin and sulfinpyrazone may increase theophylline clearance. Increased risk of seizures when used concurrently with imipenem. May potentiate hypokalaemia caused by hypoxia or when used with β-adrenoceptor stimulants, corticosteroids and diuretics. May increase the clearance of lithium.
Action
Description: Proxyphylline is a derivative of theophylline which is used as a bronchodilator and for its CV properties.
Disclaimer: This information is independently developed by MIMS based on Proxyphylline from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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