Roxithromycin - oral

Patient Medicine Information
Why do I need this medicine?
Roxithromycin is an antibiotic. It is used to treat certain bacterial infections of the throat, lungs, and skin.

This medicine may be used to treat other conditions as decided by your doctor.
How do I take this medicine?
Take Roxithromycin exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take it on an empty stomach, at least 15 minutes before or 3 hours after a meal. Try to take it at the same time each day.

This medicine is available as a tablet, capsule, or as tablet for suspension.

If you are taking the tablet for suspension, follow these steps:
  1. Remove the required number of tablet(s) from the foil. If you are taking half a tablet at a time, place the remaining half back in the foil and cover it well.
  2. Dissolve the required number of tablet(s) with at least a spoonful of water.
  3. Wait for at least 30-40 seconds for the tablet(s) to break down into fine granules, although, the tablet(s) will not be completely dissolved. If necessary, stir to disperse the granules evenly in water.
  4. Drink the suspension immediately. You may take a glass of water right after taking it.
The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type and severity of your infection.

Take Roxithromycin at regular intervals. Do not skip any doses. You must complete the entire course of this medicine. If you don't, the infection will not be properly controlled.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Do not take Roxithromycin if you ever had an allergic reaction (e.g. rashes, breathlessness, swollen eyes) to similar medicines such as azithromycin, clarithromycin, and erythromycin.

Alert your doctor if you have severe liver disease as this medicine may not be suitable for you.

Do not take Roxithromycin with medicines used to treat migraine, such as ergotamine and dihydroergotamine.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • myasthenia gravis (muscle weakness disorder)
  • heart disease
  • heart rhythm disorder e.g. congenital long QT syndrome (an inherited disease causing abnormally fast heartbeats)
  • mild to moderate liver disease
  • kidney disease
Let your doctor know if you are pregnant or breastfeeding.

Be sure to check with your doctor or pharmacist before giving Roxithromycin to a child or the elderly. Children and elderly people may be more sensitive to the side effects.

For as long as you are taking this medicine, you may need to have regular blood tests to check your body’s response to the medicine (e.g. blood counts, liver and kidney function). Your doctor will advise you about how often you need to have these tests.
What side effects could I experience?
Roxithromycin may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: headache, nausea, vomiting, diarrhoea, stomach wind, stomach pain, taste or smell disturbance, loss of appetite, and ringing in the ears.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • rashes, breathlessness, swollen face, eyes, tongue or throat
  • feeling faint, chest pain, fast or irregular heartbeat
  • fever, severe chills, sore throat or mouth ulcers
  • severe, persistent or bloody diarrhoea accompanied by severe stomach pain or fever
  • rashes with peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Do not take Roxithromycin with medicines used to treat migraine, such as ergotamine and dihydroergotamine.

Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines for irregular heartbeat e.g. disopyramide, amiodarone, digoxin
  • medicines for cold or allergy e.g. astemizole, terfenadine
  • blood-thinning medicines e.g. warfarin, phenprocoumon
  • theophylline (asthma medicine)
  • ciclosporin (medicine used in organ transplant or certain immune disorders)
  • midazolam (medicine for sleep disorder)
  • pimozide (medicine for mood disorders)
  • cisapride (medicine for digestive problems)
This list does not include all medicines that may interact with Roxithromycin.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on roxithromycin - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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