Rufinamide - oral

Patient Medicine Information
Why do I need this medicine?
Rufinamide is used together with other medicines to treat epilepsy (also known as fits or seizures) associated with Lennox-Gastaut syndrome (severe, multiple, repeated types of seizures).
How do I take this medicine?
Take Rufinamide exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take it together with food or immediately after a meal.

Rufinamide is available as a tablet or as an oral suspension.

If you are taking the tablet, swallow it whole. If you have difficulty swallowing the tablet, you may crush the tablet and mix it with half glass of water, stir and drink immediately.

If you are taking an oral suspension, shake the bottle well before you take it to ensure that the liquid is evenly mixed. Use the adapter or calibrated oral syringe provided to measure your dose.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment regimen depending on your condition, response and tolerability to Rufinamide.

This medicine must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it suddenly as this may worsen your condition.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have a heart rhythm disorder as this medicine is not suitable for you.
What should I take note of while taking this medicine?
Inform your doctor if you have liver disease.

Let your doctor know if you are pregnant or breastfeeding.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
What side effects could I experience?
Rufinamide may cause dizziness, drowsiness or some problems with your eyesight. If affected, do not drive or take part in any activity in which you need to be alert or need to see clearly.

Other side effects include any of the following: headache, tiredness, nausea, vomiting, stomach pain, constipation, decreased appetite, and flu-like symptoms.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • worsening or frequent seizures
  • signs of an allergic reaction e.g. fever, rash
  • unusual changes in mood or behaviour e.g. being depressed, having thoughts of self-harm
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • other medicines for epilepsy e.g. phenytoin, carbamazepine, lamotrigine, phenobarbital, valproate, primidone
  • medicines for difficulty sleeping e.g. triazolam
  • blood-thinning medicine e.g. warfarin
  • medicines for heart disease e.g. digoxin
Inform your doctor if you are currently taking birth control pills as this can reduce the effectiveness of Rufinamide. You should not stop or start any birth control pills without first informing your doctor. Ask your doctor about using non-hormonal birth control as an alternative while being treated with this medicine.

This list does not include all medicines that may interact with Rufinamide.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Do not take the oral suspension 90 days after it was first opened.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on rufinamide - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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